Berardinelli–Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing
نویسندگان
چکیده
منابع مشابه
Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing
OBJECTIVE To determine the role of fatty acid oxidation on the cellular, molecular, and physiologic response of brown adipose tissue to disparate paradigms of chronic thermogenic stimulation. METHODS Mice with an adipose-specific loss of Carnitine Palmitoyltransferase 2 (Cpt2A-/-), that lack mitochondrial long chain fatty acid β-oxidation, were subjected to environmental and pharmacologic int...
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ژورنال
عنوان ژورنال: Molecular Metabolism
سال: 2020
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2020.02.014